The project AVIFLU „Computational Design, Synthesis, Testing and Disposition of Inhibitors of Neuraminidazes of Influenza A Virus as Potential Antiviral Compounds“ has entered in the final months of its implementation

05.02.2022

The project AVIFLU "Computational Design, Synthesis, Testing and Disposition of Inhibitors of Neuraminidazes of Influenza A Virus as Potential Antiviral Compounds" has entered in the final months of its implementation. ICARST has contributed to the project by development of new methods of the determination of Neuraminidase inhibitory activity. 

See e.g   

Lipničanová, S., Legerská, B., Chmelová, B., Ondrejovič, M., Miertuš, S.: Optimization of an Inclusion body-based production of the influenza virus neuraminidase in Escherichia coli. Biomolecules, 12(3), 331 (2022)

Hľasová, Z., Pažitná, L., Ondrejovič, M., Katrlík, J.: Lectin-based assay for the determination of the inhibition activity of small molecule inhibitors of neuraminidase. Journal of Biotechnology, 325, 65-72 (2021)