CURRICULUM VITAE - Prof. Stanislav Miertuš

Position: Director General of ICARST n.o.

Affiliation, Address: Faculty of Natural Sciences, University of Ss. Cyril and Methodius, Nam. J. Herdu 2, Trnava 91701, Slovakia

Education (degrees, universities, dates)

1971 MSc. Faculty of Chemical and Food Technology, Slovak Technical University, Bratislava, Slovakia

1975 PhD. Polymer Institute, Slovak Academy of Science, Bratislava, Slovakia

1988 DSc. Biophysical Chemistry, Slovak Technical University, Bratislava, Slovakia

1990 Full Professor Faculty of Chemical and Food Technology, Slovak Technical University, Bratislava, Slovakia

2008 Dr.h.c. Slovak Technical University, Bratislava, Slovakia

Career, Employment (employers, positions, dates)

1971 - 1981 Slovak Academy of Science, Polymer Institute, Researcher

1981 - 1989 Slovak Technical University, Faculty of Chemical Technology, Lecturer

1989 - 1992 Full Professor, Slovak University of Technology, Faculty of Chemical Technology, Bratislava

1990 - 1992 fellow and senior researcher IIC UNIDO Trieste, Italy

1993 - 1994 Department of Chemistry and Industrial Chemistry, University of Pisa, Italy

1995 Research consultant of the ICGEB, Trieste, Italy

1994 - 1998 Project leader at Poly-Bios, AREA Science Park, Trieste, Italy

1998 Contracting Professor at Faculty of Pharmacy, University of Trieste, Italy

1998 - 2010 Area Director and deputy Managing Directer at International Centre of Science and High Technology, UNIDO, AREA Scinece Park, Trieste, Italy

2011 - present Director General, ICARST, Bratislava, Slovakia

2013 - present Professor, Faculty of Natural Sciences, University of SS. Cyril and Methodius in Trnava, Slovakia


Visiting Professor

1977 - 1979 University of Pisa, Pisa, Italy

1978 Institut de Chimie Biophysique, Paris, France

1978 University of Milan, Milan, Italy

1988 Mount Sinai School of Medicine, City Univ. of New York, USA

1992 - 1994 Department of Chemistry and Industrial Chemistry, University of Pisa, Italy


Specialization (specify)

Main field

Main interest over the last years has been in the study of catalysis, biofuels and biobased chemicals, environmentally degradable plastics, bioremediation technologies, combinatorial chemistry, computational chemistry and drug design.

Other fields

AISD research, computer modelling of biomacromolecular structure and interactions (oligo-, poly-saccharides, proteins, DNA) and drug design; biosensors development and their industrial applications in the area of food and pharmaceutical industries, biotechnology and environmental pollution monitoring. Theoretical chemistry, spectroscopy, bioanalytical chemistry.

Membership of Professional Societies

Member of American Academy of Advancement of Sciences

Member and Chairman of PAC MPOB, Kuala Lumpur, Malaysia

Member of expert group CEI, Trieste, Italy

Member of Steering Committee EC Project PLASTICE

Fellow of World Academy of Arts and Sciences, USA

Member of commision for PhD study - Applied analytical and bioanalytical chemistry, UCM, Trnava, Slovakia

Member of commsion for PhD study - Molecular biology, UCM, Trnava, Slovakia

Honorary member of Scientific Board FCHFT SUT, Bratislava, Slovakia

Member of Scientific Board, FNS, UCM, Trnava, Slovakia

Slovak Chemical Society, Slovakia

Selected Awards

Named Best Junior Researcher in Czechoslovakia (CS Academy of Sciences, Prague, 1977)

Gold Medal of vice president of Guatemala (1997)

Gold Medal of Arab Society of Materials Science, Egypt (1997)

Medal of Rega Institute Leuven, Belgium (2007)

Certificate of Recognition "Who is Who in the World" (16th and 17th "Millennium" Editions)

Doctor honoris causa, Slovak University of Technology, Bratislava, Slovakia (2008)

...

Publications

Published more than 180 publications in international scientific journals, more than 20 books and compenidia more than 9500 citations (Scopus) see also: https://www.researchgate.net/profile/Stanislav_Miertus  <H-index 30>

Selected 10 recent publications:

1. Kongkamnerd J, Cappelletti L, Prandi A, Seneci P, Rungrotmongkol T, Jongaroonngamsang N, Rojsitthisak P, Frecer V, Milani A, Cattoli G, Terregino C, Capua I, Beneduce L, Gallotta A, Pengo P, Fassina G, Miertus S, De-Eknamkul W.: Synthesis and in vitro study of novel neuraminidase inhibitors against avian influenza virus. Bioorg. Med. Chem. 20(6), 2152-7 (2012).

2. Megnassan E, Keita M, Bieri C, Esmel A, Frecer V, Miertus S.: Design of novel dihydroxynaphthoic acid inhibitors of Plasmodium falciparum lactate dehydrogenase. Med. Chem. 8(5), 970-84 (2012).

3. Owono Owono LC, Keita M, Megnassan E, Frecer V, Miertus S.: Design of Thymidine Analogues Targeting Thymidilate Kinase of Mycobacterium tuberculosis. Tuberc. Res. Treat. 2013(e670836), (2013).

4. Udommaneethanakit T, Rungrotmongkol T, Frecer V, Seneci P, Miertus S, Bren U.: Drugs against avian influenza a virus: design of novel sulfonate inhibitors of neuraminidase N1. Curr. Pharm. Des. 20(21), 3478-87 (2014).

5. Bonini C, Chiummiento L, Di Blasio N, Funicello M, Lupattelli P, Tramutola F, Berti F, Ostric A, Miertuš S, Frecer V, Kong DX.: Synthesis and biological evaluation of new simple indolic non peptidic HIV Protease inhibitors: the effect of different substitution patterns. Bioorg. Med. Chem. 22(17), 4792-802 (2014).

6. Berti F., Frecer V., Miertuš S.: Inhibitors of HIV-protease from computational design. A history of theory and synthesis still to be fully appreciated. Curr. Pharm. Des. 20(21), 3398-3411 (2014).

7. Udommaneethanakit T., Rungrotmongkol T., Frecer V., Seneci P., Miertuš S., Bren U.: Drugs against avian influenza A virus: Design of novel sulfonate inhibitors of neuraminidase N1. Curr. Pharm. Des. 20(21), 3478-3487 (2014).

8. Owono Owono, L. C., Ntie-Kang, F., Keita, M., Megnassan, E., Frecer, V., Miertuš, S.: Virtually designed triclosan-based inhibitors of enoyl-acyl carrier protein reductase of Mycobacterium tuberculosis and of Plasmodium falciparum. Mol. Inform. 34(5), 292-307 (2015).

9. Kouassi AF, Kone M, Keita M, Esmel A, Megnassan E, N'Guessan YT, Frecer V, Miertuš S.: Computer-aided design of orally bioavailable pyrrolidine carboxamide inhibitors of enoyl-acyl carrier protein reductase of Mycobacterium tuberculosis with favorable pharmacokinetic profiles. Int. J. Mol. Sci. 16(12), 29744-29771 (2015).

10. Hajzer, V., Fišera, R., Latika, A., Durmis, J., Kollár, J., Frecer, V., Tučeková, Z., Miertuš, S., Kostolanský, F., Varečková, E., Šebesta, R.: Stereoisomers of oseltamivir - synthesis, in silico prediction and biological evaluation. Org. Biomol. Chem. 15(8), 1828-1841 (2017).